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grups de recerca:

Neurobiologia i Neurogenètica dels Trastorns Afectius

Responsable: Dr. Enric Álvarez Martínez
Seu:
Servei de Psiquiatria
Hospital de la Santa Creu i Sant Pau
C/ Sant Antoni Maria Claret, 167
Accés al nou hospital: C/ Mas Casanovas, 90
08025 Barcelona
Tel. +34 932919470
email: ealvarezm@santpau.es
Components:
    - Enric Álvarez Martínez
    - Víctor Pérez Sola
    - Iluminada Corripio
    - Joaquim Soler
    - Juan Carlos Pascual
    - Dolors Puigdemont.
    - Maria Portella
    - Rosario Pérez
    - Thais Tiana.
    - Mª Teresa Castillón.
Línies de recerca:
- Relació entre els Trastorns de la son i el Trastorn depressiu major.
- Bases genètiques i neurobiològiques dels trastorns afectius.
- Estudis sobre la farmacogenètica en el tractament dels Trastorns afectius i de les esquizofrènies.
Projectes:
- Estudio Neurofisiologica de las Fobias
I. Colaborador FIS 04/2268.
- Base Neuroquimicas y geneticas del Trastorno Depresivo Mayor. I. Colaborador FIS 04/2006.
- Beca de la European Commission. European Alliance Against Depression. Duracion 2004-2007. IP V. Pérez Sola.
- Estimulación Cerebral Profunda en Depresion Mayor Resistente al tratamiento. Estudio controlado y cruzado de eficacia y tolerancia. FIS PI060662 I.P. Victor Perez Sola.
- Red de Enfermedades Mentales - Trastornos Afectivos y Psiquiátricos. RETIC 2006 RD06/0011/0015 IP Grupo Sant Pau Victor Perez Sola.
- Beca de la European Comission. European Alliance Againt Depression II. (2005323)Duración: 2007-2009 I.P. Víctor Pérez.
- Estrategias terapéuticas en Trastorno Depresivo Mayor resistente a tratamiento con Inhibidores Selectivos de la Recaptación de la Serotonina. Ensayo clínico pragmático, paralelo, aleatorizado con evaluación enmascarada. FIS EC07/90244



Publicacions:

Darbà J, Kaskens L, Pérez C, Alvarez E, Navarro-Artieda R, Sicras-Mainar A. Pharmacoeconomic Outcomes for Pregabalin: A Systematic Review in Neuropathic Pain, Generalized Anxiety Disorder, and Epilepsy from a Spanish Perspective. Advances in Therapy. 2014 Jan 4. [Epub ahead of print]

Martín-Blanco A, Soler J, Villalta L, Feliu-Soler A, Elices M, Pérez V, Arranz MJ, Ferraz L, Alvarez E, Pascual JC. Exploring the interaction between childhood maltreatment and temperamental traits on the severity of borderline personality disorder. Compr Psychiatry. 2013 Oct 22. doi:pii: S0010-440X(13)00295-2. 10.1016/j.comppsych.2013.08.026. [Epub ahead of print]

Trujols J, Feliu-Soler A, de Diego-Adeliño J, Portella MJ, Cebrià Q, Soler J, Puigdemont D, Alvarez E, Perez V. A psychometric analysis of the Clinically Useful Depression Outcome Scale (CUDOS) in Spanish patients. J Affect Disord. 2013 Dec;151(3):920-3. doi: 10.1016/j.jad.2013.08.007. Epub 2013 Aug 17.

Carrasco JL, Álvarez E, Olivares JM, Rejas J. A comparative cost-analysis of initiating pregabalin or SSRI/SNRI therapy in benzodiazepine-resistant patients with generalized anxiety disorder in Spain. Actas Esp Psiquiatr. 2013 May;41(3):164-74. Epub 2013 May 1.

de Diego-Adeliño J, Pires P, Gómez-Ansón B, Serra-Blasco M, Vives-Gilabert Y, Puigdemont D, Martín-Blanco A, Alvarez E, Pérez V, Portella MJ. Microstructural white-matter abnormalities associated with treatment resistance, severity and duration of illness in major depression. Psychol Med. 2013 Aug 21:1-12. [Epub ahead of print]

Alvarez E, Carrasco JL, Olivares JM, López-Gómez V, Vilardaga I, Perez M. Broadening of Generalized Anxiety Disorders Definition Does not Affect the Response to Psychiatric Care: Findings from the Observational ADAN Study. Clin Pract Epidemiol Ment Health. 2012;8:158-68. doi: 10.2174/1745017901208010158. Epub 2012 Nov 16.

De Salas-Cansado M, Álvarez E, Olivares JM, Carrasco JL, Ferro MB, Rejas J. Modelling the cost-effectiveness of pregabalin versus usual care in daily practice in the treatment of refractory generalised anxiety disorder in Spain. Soc Psychiatry Psychiatr Epidemiol. 2013 Jun;48(6):985-96. doi: 10.1007/s00127-012-0606-6. Epub 2012 Oct 21.

Elices M, Soler J, Fernández C, Martín-Blanco A, Jesús Portella M, Pérez V, Alvarez E, Carlos Pascual J. Physiological and self-assessed emotional responses to emotion-eliciting films in borderline personality disorder. Psychiatry Res. 2012 Dec 30;200(2-3):437-43. doi: 10.1016/j.psychres.2012.07.020. Epub 2012 Aug 9.

De Salas-Cansado M, Olivares JM, Alvarez E, Carrasco JL, Barrueta A, Rejas J. Pregabalin versus SSRIs and SNRIs in benzodiazepine-refractory outpatients with generalized anxiety disorder: a post hoc cost-effectiveness analysis in usual medical practice in Spain. Clinicoecon Outcomes Res. 2012;4:157-68. doi: 10.2147/CEOR.S31102. Epub 2012 Jun 13.

Soler J, Valdepérez A, Feliu-Soler A, Pascual JC, Portella MJ, Martín-Blanco A, Alvarez E, Pérez V. Effects of the dialectical behavioral therapy-mindfulness module on attention in patients with borderline personality disorder. Behav Res Ther. 2012 Feb;50(2):150-7. doi: 10.1016/j.brat.2011.12.002. Epub 2011 Dec 14.

Ciudad A, Álvarez E, Roca M, Baca E, Caballero L, García de Polavieja P, Casillas M, Valladares A, Gilaberte I. Early response and remission as predictors of a good outcome of a major depressive episode at 12-month follow-up: a prospective, longitudinal, observational study. J Clin Psychiatry. 2012 Feb;73(2):185-91. doi: 10.4088/JCP.10m06314. Epub 2011 Oct 4.


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